Euploid and monosomic FI hybrids for chromosomes of the 3rd and 5th homoeologic group of bread wheat cultivars Chinese Spring, Bezostaya and Mara with durum wheat cv. 788, were produced. The influence of the genotype and of the gene complexes of the above mentioned chromosomes on the chromosome pairing, as well as on the morphologic and biologic peculiarities of the hybrids was established.It was found that durum wheat possessed genetic systems similar in their effect and direction of action to those of bread wheat with considerable possibilities of reciprocal compensation in their hybrids. The hybrids obtained (and mainly those of cv. Bezostaya) with durum wheat can be used for the breeding needs of common and durum wheats.