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2003 - 153 p.

Breeding sheep for scrapie resistance

François D., Elsen J.M., Barillet F., Lajous D., Eychenne F., Palhière I.

Evidence for a genetic resistance to scrapie has been observed in different experiments conducted in the UK since the sixties, in particular the 'Sip' gene (Scrapie Incubation Period). In 1991, the relationship between the PrP gene polymorphism and the incidence of natural scrapie in several breeds was described. From 1990 to 1996, different studies showed that three codons of the gene have an action on the susceptibility to natural scrapie. The analysis of an epidemic in a French experimental farm detailed the level of susceptibility of the alleles and genotypes. In France, actions started in 1995 in dairy sheep breeds and in 1999 in meat sheep, through the survey of the frequencies of alleles and genotypes of the PrP gene in 25 breeds. In meat sheep, a few breed societies started a selection programme in 2000. In 2002 a large national programme concerning all the French breeds started.



Citer cet article    

François D., Elsen J.M., Barillet F., Lajous D., Eychenne F., Palhière I. Breeding sheep for scrapie resistance. In : Gabiña D. (ed.), Sanna S. (ed.). Breeding programmes for improving the quality and safety of products. New traits, tools, rules and organization?. Zaragoza : CIHEAM, 2003. p. 29-35. (Options Méditerranéennes : Série A. Séminaires Méditerranéens; n. 55). Meeting of the Sub-Network on Genetic Resources of the FAO-CIHEAM Inter-Regional Cooperative Research and Development Network on Sheep and Goats, 2002/05/9-11, Sassari (Italy). http://om.ciheam.org/om/pdf/a55/03600060.pdf