This research aims to screen the main phytochemicals and their antioxidant capacities from juice of some pomegranate cultivars from southern Tunisian. Total polyphenols, flavonoids, anthocyanins and hydrolysable tannins were determined by using classical spectrophotometric methods. Free radical scavenging activities were determined by DPPH and ABTS tests. Antioxidant capacities were determined by FRAP and ORAC methods. Results showed that the antioxidant potency of pomegranate extracts was correlated with their phenolic contents. In particular the highest correlations were reported between DPPH (as IC50) and respectively total flavonoids (r =-0.960), anthocyanins (r = -0.866) and total polyphenols (r=- 0.788). Therefore both total flavonoids and total anthocyanins showed high correlation to FRAP and ORAC assays. All of these findings confirm the differential contributions of pomegranate phytochemicals to the antioxidant potencies of pomegranate juice. The richness of pomegranate juice with antioxidants might encourage for the development of antioxidant function dietary food.